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AI Summary of Peer-Reviewed Research

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MuST AKT was feasible and acceptable in a pilot trial

A senior male doctor wearing a white coat and glasses uses a stethoscope to examine a female patient's arm during a consultation at a table in a modern healthcare office with green walls and shelving in the background.
Research area:MedicineRenal Transplantation Outcomes and TreatmentsOrgan Donation and Transplantation

What the study found

The MuST AKT intervention, designed to increase living donor kidney transplantation, was feasible with minor modifications and acceptable to transplant candidates and their social network.

Why the authors say this matters

The authors present MuST AKT as a way to address barriers to living donor kidney transplantation, which is a kidney transplant from a living person. The study suggests the intervention may be a workable approach for supporting communication about this option.

What the researchers tested

The researchers ran a pilot randomized controlled trial, assigning transplant candidates to standard care or the MuST AKT intervention. The intervention included four 60- to 90-minute sessions in which transplant candidates and their social network worked on barriers to living donor kidney transplantation.

What worked and what didn't

Recruitment was 61% (43 of 71), and 38 participants were randomized equally between groups. Among intervention participants who started, 1 was excluded before beginning; completion was 100% for 1 session, 94% for 2 sessions, 83% for 3 sessions, and 56% for all 4 sessions. The intervention was delivered in a mean of 71 days, shorter than anticipated, and participants reported increased confidence in communicating about living donor kidney transplantation; all recommended MuST AKT to their peers.

What to keep in mind

This was a pilot study, so the abstract focuses on feasibility and acceptability rather than definitive effects on transplantation outcomes. The abstract also notes that participants and invitees from their social network provided recommendations for improvement, but it does not describe all of those changes in detail.

Key points

  • MuST AKT was found to be feasible with minor modifications and acceptable to transplant candidates and their social network.
  • The study used a pilot randomized controlled trial comparing standard care with the MuST AKT intervention.
  • Recruitment was 61% (43 of 71), and 38 participants were randomized 1:1.
  • Among intervention participants who started, 56% completed all four sessions.
  • Participants reported increased confidence in communicating about living donor kidney transplantation, and all recommended MuST AKT to their peers.

Disclosure

Research title:
MuST AKT was feasible and acceptable in a pilot trial
Authors:
Anne-Marie Selzler, Parastoo Molla Davoodi, Scott Klarenbach, Ngan N. Lam, T. C. Smith, Abigail Ackroyd, Ben Vandermeer, Bonnie Corradetti, Aman Dhaliwal, S Ferdinand, Dorothy Ikekekpolor, Gordon Smith, Aminu K. Bello, Kevin Wen, Soroush Shojai
Institutions:
Alberta Health, Cystic Fibrosis Canada, University of Alberta, University of Calgary, Alberta Health Services, University of British Columbia
Publication date:
2026-02-25
DOI:
10.3389/ti.2026.15472
OpenAlex record:
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AI provenance: This post was generated by OpenAI. The original authors did not write or review this post.

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