Tag: Microbiome
Gut microbiome helps shape Parkinson’s drug interactions
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in PharmacologyDrug-microbiome-drug interaction study reveals how COMT inhibitors used with levodopa alter gut bacteria and affect medication metabolism in Parkinson’s patients.
Wild boar and domestic pig gut microbiomes differ by diet and lifestyle
Metagenomic analysis reveals distinct faecal microbiome structures in wild versus domesticated pigs, identifying carbohydrate-degrading taxa shaped by diet and lifestyle for probiotic development.
Human and bacterial genetics shape oral microbiome variation
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in GeneticsStudy of 12,519 individuals reveals how human genetic variants control oral microbiome composition and link to tooth decay risk through salivary enzyme abundance.
Gut microbiota metabolic reprogramming may drive metabolic disease
Dysbiosis-induced microbial metabolic reprogramming drives metabolic disease through alterations in lipid, glucose, amino acid, and uric acid metabolism.
Antibiotic use was linked to long-lasting gut microbiome changes
Population-based study linking 8-year antibiotic prescription data with fecal metagenomes in 14,979 adults to characterize associations between oral antibiotic use and gut microbiome composition.
Gut-brain signaling dysfunction is linked to age-related memory decline
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in NeuroscienceAge-associated cognitive decline driven by impaired gut-brain interoceptive signalling through microbial metabolite-induced vagal dysfunction and hippocampal neuronal dysfunction.
Ecological network balance index distinguishes healthy and dysbiotic gut states
Ecological network balance index quantifies positive and negative microbial interactions as a marker of dysbiosis, differentiating health from disease states with mechanistic grounding.
Nasal microbiome linked to small-to-modest epigenome variation in adolescents
Nasal microbiome composition shows modest but significant associations with epigenomic variation among adolescents, warranting investigation of environmental and developmental factors.
Maternal microbiota affects pregnancy outcomes and infant immune development
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in MedicineHow maternal and infant gut microbiomes shape pregnancy outcomes, immune development, and long-term health during the critical first 1000 days of life.
Hirschsprung disease shows distinct gut microbiota shifts after surgery
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in MedicineLongitudinal study identifies distinct gut microbiota alterations in Hirschsprung disease patients, revealing bacterial markers for postoperative enterocolitis risk.
