Tag: Analytical Chemistry and Chromatography
RP-HPLC accurately quantified metoprolol and enalapril maleate
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in ChemistryRP-HPLC method for simultaneous quantification of metoprolol and enalapril maleate using environmentally sustainable approach with recovery rates of 98–102% and validation per ICH criteria.
Composite cryogel column enabled selective L-phenylalanine separation
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Composite cryogel column with molecularly imprinted microparticles achieves selective L-phenylalanine separation with 39.40 mg/g adsorption capacity and reusability.
HILIC-DIA-MS enabled analysis of polar peptides in foods
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HILIC-DIA-MS workflow for targeted and untargeted analysis of polar peptides and taste-relevant compounds in foods including cheese, ham, and fermented products.
Trace ethylene boosts nitrogen GC-MS sensitivity
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Adding trace ethylene to nitrogen carrier gas in GC-MS increases sensitivity 20-fold while maintaining 70 eV electron-ionization spectral patterns compatible with existing reference libraries.
RFS mode improved chromatography efficiency and lowered pressure
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Novel radial flow stream splitting HPLC columns reduce analysis time by 40 percent while maintaining quantitative accuracy for pharmaceutical drug testing.
HS-GC-IMS is described as a greener, efficient cocoa analysis approach
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in ChemistryHydrogen-based GC-IMS combined with machine learning enables rapid, sustainable classification of cocoa by geographic origin without sample preparation.
Miniaturized extraction selectively enriched toxicologically relevant MOAH
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in ChemistryMiniaturized extraction selectively enriches trace polycyclic aromatics in mineral oils, improving detection of genotoxic compounds masked by abundant alkylated aromatics in complex mixtures.
HPTLC method reliably measured gentamicin sulphate in ointment
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Stability-indicating HPTLC method validated for gentamicin sulphate quantification in ointments, requiring no sample extraction and showing high linearity and sensitivity.
Hyperbranched polymers show a branching-dependent adsorption transition
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in ChemistryHyperbranched polystyrene exhibits nonuniversal exclusion-to-adsorption transitions in chromatography, governed by branching density and fractal dimension, diverging from linear polymer behavior.
Dual cyclodextrin systems support chiral separations in EKC
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in ChemistryDual-cyclodextrin systems in electrokinetic chromatography enhance chiral resolution for pharmaceutical, biological, and environmental analyses with model-based optimization.
