Tag: Analytical Chemistry and Chromatography

Headspace gas chromatography may support food authenticity analysis
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in Chromatography
Static headspace sampling with cryogenic modulation GC×GC-TOFMS enables comprehensive volatile and chiral analysis of citrus essential oils, eliminating solvents while improving detectability for.
Light-controlled cellulose sorbent enabled amphetamine extraction
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in Chemistry
Light-driven cellulose-azobenzene sorbent for amphetamine extraction with UV-triggered 90% desorption efficiency and validated HPLC-UV method.
Validated HPLC method estimates three tea phytoconstituents
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in Chromatography
RP-HPLC method development and validation for simultaneous determination of caffeine, eugenol, and zingerone in Ashwagandha green tea using Design of Experiments and ICH guidelines.
Validated HPLC method measures polysorbate 80 in mAbs
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in Chemistry
Interlaboratory validated HPLC-ELSD method for accurate polysorbate 80 quantification in monoclonal antibody formulations with robust performance across diverse laboratory settings.
Ultrathin chiral nanosheets improved gas chromatography separations
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in Chemistry
Ultrathin 2D nanosheets from exfoliated chiral ionic organic crystals enable high-resolution gas chromatography with exceptional enantioselectivity for pharmaceutical compound separation.
AQbD improved peptide separation and produced a green UHPLC-ToF-MS method
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in Chromatography
AQbD-based UHPLC-ToF-MS method for simultaneous analysis of synthetic peptides, incorporating design space definition and greenness assessment for robust analytical characterization.
Method distinguishes chiral α-hydroxy acids in complex samples
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in Chemistry
MALDI-TIMS-MS platform with chiral derivatization for enantiomeric discrimination of α-hydroxy acids in tumor tissues and food samples with sensitivity to 5.8% enantiomeric ratios.
Validated HPLC method for clofazimine and pyrazinamide analysis
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in Chromatography
RP-DAD-HPLC method development and ICH Q2 validation for simultaneous quantitative analysis of clofazimine and pyrazinamide in fixed-dose combination topical delivery systems.