Category: Organic chemistry
Peppermint tea extract was rich in terpenes
Analysis of commercial peppermint tea extracts identified 16 previously unreported volatile compounds and showed that the aqueous extract volatile profile differs from essential oil composition.
Organic-dye CDC method adds fluoronitromethane to tetrahydroisoquinolines
Organocatalytic cross-dehydrogenative coupling of tetrahydroisoquinolines with fluoronitromethane using Rose Bengal and green LED irradiation for sustainable fluorinated compound synthesis.
Three-layer strategy produces fused hydantoins and diketopiperazines
A scalable three-layer synthesis strategy rapidly produces thiazolo-hydantoins and diketopiperazines in under 3 hours without chromatography, enabling one-pot processing and late-stage modification.
New sulfanyl indeno triazinones were synthesized and some cyclized further
Novel one-pot synthesis of 3-alkenyl(propargyl)sulfanyl-indeno[1,2-e][1,2,4]triazin-9-ones with selective heterocyclization through halogenation.
Misconceptions were linked to lower organic chemistry self-efficacy
Study reveals that foundational chemistry misconceptions significantly predict lower self-efficacy in college organic chemistry, with implications for early intervention strategies.
Oxoammonium catalysis enables enantioselective desymmetrization of meso-pyrrolidines
Oxoammonium-catalyzed desymmetrization of meso-pyrrolidines via enantioselective hydride transfer with over 90% ee, featuring mechanistic insights from isolated intermediates.
Modular synthesis of CF3/CHF2 dihydroquinoline sulfonyl fluorides
Modular synthesis of CF3/CHF2-substituted dihydroquinoline sulfonyl fluorides via [4+2] cycloaddition and sulfur(VI) fluoride exchange without transition metal catalysis.
Structural modification improved catechin antioxidant and lipid-solubility traits
DFT computational study reveals how structural modifications of catechins enhance antioxidant activity and lipid solubility simultaneously, overcoming traditional polarity-bioavailability.
Organocatalytic method esterifies P(O)–OH compounds with alcohols
Organocatalytic metal-free esterification of phosphoryl compounds with alcohols via catalytic Mitsunobu protocol, yielding phosphinate esters with broad functional group tolerance.
Indole-based synthesis yields α-perfluoroalkylamino derivatives
Novel sequential perfluoroalkylation and defluoroamination of indoles via sulfinate-derived radicals and HMDS-mediated C-F cleavage, yielding α-trifluoromethylated amines in up to 80% yield.
