Category: Organic chemistry
Thiolate-mediated cyclization yields 2-quinolones from aminocinnamic acids
Thiolate-mediated cyclization protocol for synthesis of 2-quinolones and 2-aza-quinolones from aminocinnamic acid derivatives with broad substrate scope and gram-scale scalability.
2-Lithiomethylindoles enable diverse 2-functionalized indoles
Optimized α-lithiation protocol for 1,2-dimethylindoles enables efficient C2-functionalization via diverse electrophile trapping in deep eutectic solvents under air-tolerant conditions.
Pyridinium catalysis enables stereoselective 2-deoxy-2-fluoroglycoside assembly
Pyridinium-catalyzed stereoselective synthesis of 2-deoxy-2-fluoroglycosides via syn-addition to 2-fluoroglycals with mechanistic insights from NMR and DFT studies.
