Tag: Analytical Chemistry
RP-HPLC accurately quantified metoprolol and enalapril maleate
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in ChemistryRP-HPLC method for simultaneous quantification of metoprolol and enalapril maleate using environmentally sustainable approach with recovery rates of 98–102% and validation per ICH criteria.
Composite cryogel column enabled selective L-phenylalanine separation
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Composite cryogel column with molecularly imprinted microparticles achieves selective L-phenylalanine separation with 39.40 mg/g adsorption capacity and reusability.
RFS mode improved chromatography efficiency and lowered pressure
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Novel radial flow stream splitting HPLC columns reduce analysis time by 40 percent while maintaining quantitative accuracy for pharmaceutical drug testing.
Miniaturized extraction selectively enriched toxicologically relevant MOAH
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in ChemistryMiniaturized extraction selectively enriches trace polycyclic aromatics in mineral oils, improving detection of genotoxic compounds masked by abundant alkylated aromatics in complex mixtures.
Aromatic Indian teas showed stronger bioactivity in several tests
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in BiochemistryHPTLC analysis and molecular docking reveal that spice-enriched Indian black teas contain elevated phenolic compounds with strong antioxidant and antidiabetic activity in cellular assays.
HPTLC method reliably measured gentamicin sulphate in ointment
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Stability-indicating HPTLC method validated for gentamicin sulphate quantification in ointments, requiring no sample extraction and showing high linearity and sensitivity.
Dual cyclodextrin systems support chiral separations in EKC
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in ChemistryDual-cyclodextrin systems in electrokinetic chromatography enhance chiral resolution for pharmaceutical, biological, and environmental analyses with model-based optimization.
Light-controlled cellulose sorbent enabled amphetamine extraction
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in ChemistryLight-driven cellulose-azobenzene sorbent for amphetamine extraction with UV-triggered 90% desorption efficiency and validated HPLC-UV method.
Validated HPLC method estimates three tea phytoconstituents
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RP-HPLC method development and validation for simultaneous determination of caffeine, eugenol, and zingerone in Ashwagandha green tea using Design of Experiments and ICH guidelines.
Validated HPLC method measures polysorbate 80 in mAbs
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in ChemistryInterlaboratory validated HPLC-ELSD method for accurate polysorbate 80 quantification in monoclonal antibody formulations with robust performance across diverse laboratory settings.
