Category: Neuroscience
Cross-domain hearing test battery provides age- and PTA-based norms
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in NeuroscienceWhat the study found The study found that a clinically feasible audiological-vestibular test battery can provide normative values for characterizing age-related hearing loss. It also found age- and pure-tone average (PTA, a basic measure of hearing threshold level across frequencies) dependent reference data for the tested measures. Why the authors say this matters The authors…
Basal ganglia PVS linked to longitudinal cognitive decline
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in NeuroscienceWhat the study found Higher MRI-visible perivascular space (PVS) burden in the basal ganglia, a deep brain region, was associated with worse cognitive performance over time. The strongest independent associations remained for executive function and visuospatial skills. Why the authors say this matters The authors conclude that basal ganglia PVS may be an emerging marker…
Brief electrical stimulation induced ketamine-like plasticity in human neurons
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in NeuroscienceBrief electrical stimulation produces ketamine-like structural plasticity in human dopamine neurons via calcium-dependent BDNF and mTOR signaling, reversing cortisol-induced damage.
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
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in NeuroscienceStudy reveals how elevated DNA damage and impaired repair mechanisms drive selective vulnerability of cortical neurons in MS and neuroinflammation.
mPFC pathways show distinct affective state patterns
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in NeuroscienceCalcium imaging reveals distinct activity patterns in mPFC pathways to amygdala versus nucleus accumbens during anxiety, exploration, and social behaviors in mice.
Touch-based speed-constant material perception relies on natural statistics
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in NeuroscienceNatural material surfaces produce speed-invariant vibration signatures that explain how humans perceive materials consistently. The spectral exponent relates to tactile receptor activation.
Emotion regulation success tracks large-scale brain gradient reconfiguration
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in NeuroscienceGradient-based analysis of brain organization reveals that emotion regulation success involves systematic reconfigurations along a hierarchy from sensory to integrative regions.
Autistic adults showed more forward waves during visual stimulation
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in NeuroscienceEEG study reveals autistic adults show enhanced forward traveling waves during visual entrainment, suggesting reduced top-down predictions and increased bottom-up sensory processing compared to.
Effort boosts dopamine release through acetylcholine
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in NeuroscienceEffort amplifies dopamine reward responses through acetylcholine modulation of dopamine axons in the nucleus accumbens, explaining how organisms maintain reward-seeking under resource constraints.
Trust and anticipation drive delight in gaming reviews
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in NeuroscienceStudy of 2.4M gaming reviews reveals how design features build consumer trust, which drives anticipation and delight through distinct psychological pathways.
