Tag: In vitro
Gut microbiome helps shape Parkinson’s drug interactions
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in PharmacologyDrug-microbiome-drug interaction study reveals how COMT inhibitors used with levodopa alter gut bacteria and affect medication metabolism in Parkinson’s patients.
Aromatic Indian teas showed stronger bioactivity in several tests
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in BiochemistryHPTLC analysis and molecular docking reveal that spice-enriched Indian black teas contain elevated phenolic compounds with strong antioxidant and antidiabetic activity in cellular assays.
AOH1996 remained the most active PCNA inhibitor analog
Synthesis and anticancer evaluation of PCNA inhibitor AOH1996 analogs in MCF-7 and U87 cancer cell cultures with SAR analysis and ADMET prediction
Human Pol-PCNA binds DNA in an unexpected extra site
Cryo-EM re-evaluation of human DNA polymerase epsilon-PCNA reveals unexpected multi-site DNA binding behavior contradicting prior mechanistic interpretations of mismatch recognition and proofreading.
Thermal treatments changed black wheat flour properties and digestibility
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in Food scienceStudy on thermal modifications of black wheat flour examining effects on structure, digestibility, and functional properties using microwaving, roasting, and heat fluidization.
Prunus africana bark extract showed selective cytotoxicity in prostate cancer cells
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In vitro evaluation of Prunus africana extract cytotoxicity on hormonally insensitive prostate cancer C4-2 cells via apoptosis-mediated mechanisms.
