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AI Summary of Peer-Reviewed Research

This page presents an AI-generated summary of a published research paper. The original authors did not write or review this article. [See full disclosure ↓]

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Rare solitary fibrous tumor found in the floor of the mouth

A histological cross-section of tissue mounted on a microscope slide, stained with purple and blue dyes, showing cellular and tissue organization under magnification in a pathology laboratory setting.
Research area:PathologyOral and Maxillofacial PathologySoft tissue tumor case studies

What the study found

A solitary fibrous tumour (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was identified in the floor of the mouth, which the authors describe as a particularly rare intraoral site. The case involved a 42-year-old man with a slow-growing mass on the left side of the floor of the mouth.

Why the authors say this matters

The authors conclude that this case highlights a rare intraoral presentation of SFT and underscores the importance of histopathological assessment supported by STAT6 immunohistochemistry for accurate diagnosis. They present this as relevant because SFT in this location is uncommon.

What the researchers tested

The article reports a single case of a 42-year-old man with a well-circumscribed mass in the floor of the mouth. The lesion was examined grossly, then studied histologically and with immunohistochemical testing, including CD34 and STAT6.

What worked and what didn't

Gross examination showed an encapsulated pink-greyish mass measuring 3.3 cm. Histology showed uniform spindle cells in a patternless architecture within variably collagenized stroma, with prominent thin-walled branching vessels. Immunohistochemistry showed diffuse CD34 positivity and strong nuclear STAT6 expression, which confirmed the diagnosis of solitary fibrous tumour.

What to keep in mind

This is a single case report, so it describes one patient rather than a broader group. The abstract does not describe treatment, follow-up, or additional limitations beyond the rarity of the site.

Key points

  • The case involved a 42-year-old man with a slow-growing mass in the floor of the mouth.
  • The mass measured 3.3 cm and was described as encapsulated and pink-greyish.
  • Histology showed spindle cells, patternless architecture, collagenized stroma, and thin-walled branching vessels.
  • CD34 positivity and strong nuclear STAT6 expression confirmed the diagnosis of solitary fibrous tumour.
  • The authors describe floor-of-mouth SFT as a particularly rare intraoral presentation.

Disclosure

Research title:
Rare solitary fibrous tumor found in the floor of the mouth
Authors:
Meriem Boubekri, Mohamed Amine Essaoudi, Amal Damiri, Hafsa Chahdi, Mohamed Oukabli
Institutions:
Mohammed V University
Publication date:
2026-02-24
DOI:
10.1016/j.adoms.2026.100649
OpenAlex record:
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AI provenance: This post was generated by OpenAI. The original authors did not write or review this post.

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