Focal Interest
Focal Interest

Kidney transplantation

  1. Donor ventilation time was not linked to 1-year lung function
    Evidence suggests prolonged donor mechanical ventilation does not impair recipient lung function after transplant, challenging traditional donor selection practices in lung transplantation.
  2. Pediatric transplantation in China increased under new allocation rules
    Review of pediatric organ transplantation trends in China from 2015-2024, examining volumes, outcomes, regulatory frameworks, and challenges under reformed donation systems.
  3. Donor TNFα linked to worse kidney graft outcomes
    High circulating tumor necrosis factor α in deceased organ donors associates with inferior kidney graft function and survival after transplantation through TNFR1-mediated injury mechanisms.
  4. MuST AKT was feasible and acceptable in a pilot trial
    MuST AKT pilot trial tests structured intervention to increase living donor kidney transplants through multidisciplinary support and social network engagement.
  5. Wait time policy increased transplant rates for Black candidates
    Quasi-experimental evaluation of wait time modification policy effects on Black kidney transplant candidates, addressing race-based kidney function estimation bias in allocation algorithms.
  6. Mild AKI in elderly kidney donors did not worsen graft outcomes
    Kidney transplantation from elderly donors with mild acute kidney injury yields comparable graft survival and function to non-AKI donors, supporting expanded utilization in recipient selection.
  7. XGBoost performed best for predicting late eGFR after kidney transplant
    Machine learning models combined with Monte Carlo simulation predict late kidney transplant function using tacrolimus pharmacokinetics and clinical parameters.