Concept: DNA Repair Mechanisms
Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
Resistance mechanisms to PARP inhibitor therapy in BRCA-mutant breast cancer
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
DNA damage burden drives selective loss of cortical neurons in multiple sclerosis
Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair
DNA repair adaptations enable evolutionary expansion of upper brain layers
PAF15-PCNA exhaustion limits strand-specific DNA replication control
How a protein complex limits DNA replication when origins fire excessively
Mycobacterial gyrase inhibition depends on DNA topology
How drug interactions with DNA topology affect gyrase inhibition in mycobacteria
BrDMC1 helps pollen meiosis tolerate heat in Brassica rapa
Heat-tolerance gene enhances pollen survival in stressed crops
Complex chromosome 6 inversions produced recombinant offspring
Complex inversions on chromosome 6 produce unexpected recombinant chromosomes in affected children
A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric Proteins
Analyzing how a telomere-protecting protein recognizes DNA junctions using high-throughput screening
AOH1996 remained the most active PCNA inhibitor analog
Novel compounds targeting a key cancer cell protein show promise in reducing cell growth
Mitotic repair pathway drives chromoanasynthesis
A mitotic DNA repair process explains how complex chromosome rearrangements form in cancer
