Category: Stereochemistry
Desymmetrization method forms N–N atropisomers with multiple stereocenters
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Asymmetric Michael addition constructs N-N atropisomers from indole-derived maleimides with simultaneous generation of multiple stereocenters, achieving 99% yield and exceptional stereoselectivity.
Chiral carbon-bonding donors showed asymmetric induction
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Carbon-bonding donors induce asymmetric induction via noncovalent interaction, demonstrated through oxa-Pictet-Spengler cyclization with oxocarbenium intermediates.
