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Cross-domain hearing test battery provides age- and PTA-based norms

Research area:NeuroscienceSensory SystemsVestibular and auditory disorders

What the study found

The study found that a clinically feasible audiological-vestibular test battery can provide normative values for characterizing age-related hearing loss. It also found age- and pure-tone average (PTA, a basic measure of hearing threshold level across frequencies) dependent reference data for the tested measures.

Why the authors say this matters

The authors say this matters because the study provides measures that can support more precise phenotyping of hearing loss beyond audibility alone. They also state that age and PTA should be considered as covariates in future applications such as phenotype-genotype relations in specified cohorts.

What the researchers tested

The researchers proposed a comprehensive audiological-vestibular test battery through multidisciplinary consensus. They then analyzed center effects between Germany and France to check comparability, and examined age and PTA effects for each test in 55 participants aged 40 years or older with hearing thresholds better than the age-dependent median of PTA.

What worked and what didn't

Center effects were negligible, so the data from the two centers were pooled. Age and PTA effects were identified for some tests, especially audiological-functional tests, while no age effects were found for vestibular tests.

What to keep in mind

The abstract does not describe detailed limitations beyond noting the need for extensive data documentation and verification for cross-center comparability. The reference data were derived from a specific group of age-appropriate normal-hearing controls, so the reported norms apply to that sample and testing framework.

Key points

  • The study provided normative values for a multidimensional audiological-vestibular test battery.
  • Age- and PTA-dependent reference data were derived from 55 participants aged 40 years or older.
  • Negligible center effects allowed pooling of data from German and French sites.
  • Age and PTA effects appeared in some tests, especially audiological-functional measures.
  • No age effects were found for vestibular tests.
  • The authors say age and PTA should be considered in future interpretations of these tests.

Disclosure

Research title:
Cross-domain hearing test battery provides age- and PTA-based norms
Authors:
Mareike Buhl, Shiran Koifman, Abile Serge Magbonde, Koray Koçoğlu, Sabine Hochmuth, Elie Partouche, Arnaud Coëz, Andreas Radeloff, Hung Thaï-Van, Sylvette Wiener‐Vacher, Grégory Gerenton, Anna Warzybok, Paul Avan, Birger Kollmeier
Institutions:
Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Assistance Publique – Hôpitaux de Paris, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Universität Oldenburg, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Centre National de la Recherche Scientifique, Générale de Santé, Hearing4all, Hearing4all, Hearing4all, Hearing4all, Hearing4all, Hôpital Edouard Herriot, Hospices Civils de Lyon, Inserm, Inserm, Inserm, Inserm, Inserm, Inserm, Inserm, Inserm, Inserm, Institut de France, Institut de France, Institut de France, Institut de France, Institut de France, Institut de France, Institut de France, Institut de France, Institut de France, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Institut Pasteur, Oldenburger Institut für Informatik, Oldenburger Institut für Informatik, Oldenburger Institut für Informatik, Oldenburger Institut für Informatik, Oldenburger Institut für Informatik, Université Claude Bernard Lyon 1, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité
Publication date:
2026-04-22
OpenAlex record:
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