Tag: Treatment of Major Depression
Molecular imaging links late-life depression to neurotransmitter and Alzheimer’s changes
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in MedicineMolecular imaging reveals late-life depression involves altered neurotransmitter systems, Alzheimer’s pathology, and neuroinflammation, supporting development of targeted mechanism-based treatments.
Zuranolone was approved for postpartum depression, not major depressive disorder
Analysis of zuranolone approval reveals how fast-track designations and reduced evidentiary thresholds in drug regulation may inadequately balance innovation with public health protection.
Reasoning-based LLMs may predict antidepressant response
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in PsychiatryStudy evaluates reasoning-based large language models for predicting 12-week remission in depressive disorder patients undergoing antidepressant monotherapy.
Baseline severity, prior care, and attendance linked to CBT symptom change
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in PsychologyObservational primary-care CBT analysis: higher baseline severity linked to greater absolute symptom reduction; total session count, not attendance rate, predicts outcomes; waiting time showed no.
