Tag: Osteomyelitis and Bone Disorders Research

What the study found Tmem178, a protein that limits calcium (Ca2+) entry by restraining store-operated calcium entry, suppresses NLRP3 inflammasome activation in osteoclasts, the bone-resorbing cells. The abstract states that this restraint also limits the bone-resorbing activity of osteoclasts. Why the authors say this matters The authors conclude that Tmem178 potently restricts Ca2+ influx in…