Tag: Mass Spectrometry Techniques and Applications
Trace ethylene boosts nitrogen GC-MS sensitivity
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Adding trace ethylene to nitrogen carrier gas in GC-MS increases sensitivity 20-fold while maintaining 70 eV electron-ionization spectral patterns compatible with existing reference libraries.
Functional groups strongly affect amino acid LC-MS derivatization
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in ChemistrySystematic evaluation of derivatization agents for LC-MS amino acid analysis identifies isoquinoline-6-carboxylic acid NHS ester as optimal, achieving nanomolar sensitivity and long-term stability.
Method distinguishes chiral α-hydroxy acids in complex samples
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in ChemistryMALDI-TIMS-MS platform with chiral derivatization for enantiomeric discrimination of α-hydroxy acids in tumor tissues and food samples with sensitivity to 5.8% enantiomeric ratios.
