Tag: Lung cancer

Fibroblast lipid cues shape squamous cell carcinoma invasion
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in Biochemistry, Genetics and Molecular Biology
What the study found Fibroblasts from different tissue sites provide site-specific lipid cues that influence squamous cell carcinoma (SCC) proliferation and invasion. Oral and lung fibroblasts transfer different lipids to SCC cells, while dermal fibroblasts are described as lipid poor. Why the authors say this matters The authors conclude that these fibroblast lipid cues help…
FMT with immunotherapy showed activity in NSCLC and melanoma
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in Oncology
Phase 2 trial: donor FMT plus first-line ICI in NSCLC and melanoma showed high ORRs and implicates loss of specific bacterial taxa in association with response.

Fibroblast lipid cues shape squamous cell carcinoma invasion