Tag: Enzyme
Mycobacterial gyrase inhibition depends on DNA topology
Study reveals that antibacterial drugs inhibit different gyrase-mediated catalytic activities at varying concentrations, with DNA topology modulating drug potency beyond DNA cleavage mechanisms.
Fermentation changes polyphenols into more bioactive metabolites
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in Food scienceReview examining how microbial fermentation converts plant polyphenols into bioavailable metabolites that enhance gut health and systemic immune function through selective microbiota modulation.
Cryo-EM reveals multiple cytochrome P450 reductase conformations
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in Biochemistry3.3 Å cryo-EM of full-length rat cytochrome P450 reductase reveals a relaxed compact state, additional compact variants, and ~20% of particles with displaced or missing FMN domain.
