Tag: Cancer

Higher CKM stage was linked to higher cancer risk
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in Medicine
What the study found Advancing cardiovascular-kidney-metabolic (CKM) syndrome stage was associated with higher cancer risk, especially at Stages 3 and 4. The association was reported in a large nationwide population and was consistent across cancer types and several subgroup analyses. Why the authors say this matters The authors conclude that the findings extend the clinical…
Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
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in Oncology
Study identifies BRN2-mediated and SHLD2-related resistance to talazoparib in BRCA-mutant breast cancer, proposing combination therapy approaches to improve neoadjuvant treatment outcomes.
U.S. cancer mortality declines varied by county income and location
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in Medicine
County-level analysis reveals disparities in cancer mortality decline across geography, income, and urbanization in the United States.
RPA reduced cancer registry abstraction time in a hospital EHR system
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in Engineering
RPA implementation for cancer registry data abstraction achieved 74% time reduction in gastric cancer and 30% in breast cancer, with success dependent on clinician cooperation and output monitoring.
Participants weighed privacy against potential value of browsing history research
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in Health Sciences
Qualitative study examines acceptability of sharing internet browsing history for cancer research among diverse populations, identifying trust and transparency as key factors.
Wartime Ukraine cancer care largely recovered near pre-war levels
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in Social Sciences
Study examines Ukrainian oncology system’s resilience during Russian invasion, documenting rapid recovery mechanisms, international partnerships and persistent barriers to equitable care access.
Hypodermoclysis appears generally safe in advanced cancer
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in Medicine
Hypodermoclysis shows favorable safety and feasibility for hydration in advanced cancer patients receiving palliative care, with mild complications in 17% of cases and no consistent survival benefits.
PFOA-linked bladder cancer signals identified in transcriptomic analysis
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in Cancer research
Study reveals molecular mechanisms linking PFOA exposure to bladder cancer through integrative toxicogenomics and gene expression analysis, identifying key transcriptional signatures for cancer.
Gut microbiome is linked to colorectal cancer development and management
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in Cancer research
Review of gut microbiome mechanisms in colorectal cancer carcinogenesis, examining pathogenic bacteria, protective functions, biomarker development, and therapeutic strategies.
Older Iranian adults with colorectal cancer reported layered existential distress
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in Medicine
Explore how existential distress among older Iranian adults with colorectal cancer is shaped by personal beliefs and sociocultural values, and the need for culturally informed cancer care.