What the study found
PCORnet is presented as a national research resource that has supported a large number of studies over the past 10 years. The abstract reports that more than 300 studies have been completed using the infrastructure, including 58 that earned meritorious PCORnet Study status, with 19 of those completed.
Why the authors say this matters
The authors say PCORnet is designed to enhance the nation's capacity to conduct efficient, patient-centered health research. They conclude that the infrastructure offers unique capabilities for supporting innovation in future trials and can be part of a continuously learning framework.
What the researchers tested
The article describes PCORnet infrastructure and the kinds of study designs it can support, including a subset called PCORnet Studies that must meet specific criteria and approval. The authors also review several completed efforts, their study archetypes, therapeutic areas, funding sources, and the range of institutions using PCORnet.
What worked and what didn't
The abstract reports that the infrastructure has been used across many studies and that 58 studies met the meritorious PCORnet Study distinction. It also says 19 of those meritorious studies have been completed. The abstract does not describe specific comparisons, failures, or which study approaches worked best.
What to keep in mind
The available summary does not provide detailed study outcomes, specific methods for each study, or direct evidence comparing PCORnet with other research systems. It also does not list limitations beyond noting that the article draws on accumulated experience and selected examples.
Key points
- PCORnet is described as a national resource for patient-centered health research.
- More than 300 studies have been completed using the PCORnet infrastructure over 10 years.
- Fifty-eight studies earned meritorious PCORnet Study status, and 19 of those were completed.
- The authors say PCORnet can support a variety of study designs and future trial innovation.
- The abstract highlights study archetypes, therapeutic areas, funding sources, and institutional users.
Disclosure
- Research title:
- PCORnet supported many studies and several meritorious ones
- Authors:
- Adrian F. Hernandez, Elizabeth Shenkman, Kathleen McTigue, Lisa Kepler, Lauren W. Cohen, Mónica Pérez Jolles, Russell L. Rothman, Jason P. Block, Thomas W. Carton, Jonathan N. Tobin, Elisa L. Priest, Crystal Evans, John Heintzman, David A. Williams
- Institutions:
- Duke University, Clinical Research Institute, University of Florida, University of Pittsburgh, University of Colorado Denver, Vanderbilt University Medical Center, Harvard Pilgrim Health Care, Louisiana Public Health Institute, Clinical Directors Network, Rockefeller University, Baylor Scott & White Health, Oregon Health & Science University
- Publication date:
- 2026-01-08
- OpenAlex record:
- View
Get the weekly research newsletter
Stay current with peer-reviewed research without reading academic papers — one filtered digest, every Friday.