Concept: Microtubule and mitosis dynamics

PAF15-PCNA exhaustion limits strand-specific DNA replication control
How a protein complex limits DNA replication when origins fire excessively
April 8, 2026
Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks
How cells prevent DNA breaks from clustering together across the genome
March 23, 2026
Image Credit: Photo by National Cancer Institute on Unsplash (Source • License)
CTF18-RFC structure reveals how it binds PCNA
Molecular structure reveals how a key protein complex loads DNA replication machinery
March 14, 2026
Bora links Aurora-A activation to PLK1 recognition
How a protein bridges two kinases to trigger cell division
March 11, 2026
Chromosome-specific differences in the recombination landscape of spontaneous meiotic nondisjunction
How crossover patterns differ across chromosome types during meiotic failures
March 9, 2026
Image Credit: AI-generated image (OpenAI / DALL·E)