Concept: Homologous recombination

Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
Resistance mechanisms to PARP inhibitor therapy in BRCA-mutant breast cancer
April 17, 2026
Complex chromosome 6 inversions produced recombinant offspring
Complex inversions on chromosome 6 produce unexpected recombinant chromosomes in affected children
April 6, 2026
Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks
How cells prevent DNA breaks from clustering together across the genome
March 23, 2026
Image Credit: Photo by National Cancer Institute on Unsplash (Source • License)
Chromosome-specific differences in the recombination landscape of spontaneous meiotic nondisjunction
How crossover patterns differ across chromosome types during meiotic failures
March 9, 2026
Image Credit: AI-generated image (OpenAI / DALL·E)