Concept: DNA polymerase
PAF15-PCNA exhaustion limits strand-specific DNA replication control
How a protein complex limits DNA replication when origins fire excessively
Human Pol-PCNA binds DNA in an unexpected extra site
Structural models need revision based on unexpected enzyme behavior in laboratory tests
CTF18-RFC structure reveals how it binds PCNA
Molecular structure reveals how a key protein complex loads DNA replication machinery
