Concept: Cancer therapeutics and mechanisms
Enzyme–DNA Interactions Affect the Catalytic Inhibition of Mycobacterial Gyrases by Antibacterial Drugs
How drug interactions with DNA topology affect gyrase inhibition in mycobacteria
AOH1996 remained the most active PCNA inhibitor analog
Novel compounds targeting a key cancer cell protein show promise in reducing cell growth
Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks
How cells prevent DNA breaks from clustering together across the genome
