Focal Interest
Focal Interest
AI Summary of Peer-Reviewed Research

This page presents an AI-generated summary of a published research paper. The original authors did not write or review this article. [See full disclosure ↓]

Publishing process signals: STRONG — reflects the venue and review process. — venue and review process.

Donor acceptance patterns in pancreas transplant changed over time

A black and white historical photograph showing six medical professionals wearing long white coats and head coverings gathered around a table in what appears to be a clinical setting, with one person examining or discussing a document or patient material while others observe.
Research area:MedicineOrgan Donation and TransplantationTransplantation

What the study found

The study found significant shifts in how donor organs were accepted for pancreas transplant over time. It reported growing reluctance to use donation after circulatory death (DCD) donors, despite favourable outcomes, alongside increasing acceptance of Hepatitis C positive and intravenous drug use (IVDU) donors.

Why the authors say this matters

The authors conclude that the reluctance to use DCD donors is a valuable area to focus pancreas utilisation efforts in the United States. They also suggest that the growing acceptance of Hepatitis C positive and IVDU donors supports expanding these donor populations globally.

What the researchers tested

The paper describes a large population cohort study examining donor factors influencing pancreas transplant utilisation and how decision-making evolved over time. The abstract does not provide further details about the cohort definition, setting, or specific analytic methods.

What worked and what didn't

The study reports increasing acceptance of previously underused donor groups, specifically Hepatitis C positive and IVDU donors. At the same time, it found increasing reluctance to use DCD donors, even though the abstract states there was evidence of favourable outcomes for those donors.

What to keep in mind

The available summary does not describe the study's limitations, the time period studied, or detailed outcome measures. The abstract also does not provide the numerical results or full methods needed to assess the strength of the findings.

Key points

  • The study found significant shifts in pancreas transplant donor acceptance over time.
  • Use of donation after circulatory death (DCD) donors became more reluctant despite favourable outcomes.
  • Acceptance increased for Hepatitis C positive donors and intravenous drug use (IVDU) donors.
  • The authors say DCD donor reluctance is a useful area to target in U.S. pancreas utilisation efforts.
  • The abstract does not describe detailed methods, limits, or numerical results.

Disclosure

Research title:
Donor acceptance patterns in pancreas transplant changed over time
Authors:
Chahana A Patel, Georgios Kourounis, Leonie van Leeuwen, Matthew L. Holzner, Vikram Wadhera, M.Z. Akhtar, Sander S. Florman, Angeles Maillo-Nieto, James Shaw, Steven White, Colin Wilson, Samuel James Tingle
Institutions:
Freeman Hospital, NIHR Newcastle Biomedical Research Centre, Newcastle University, NHS Blood and Transplant, Mount Sinai Hospital
Publication date:
2026-03-07
DOI:
10.1038/s43856-026-01506-9
OpenAlex record:
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AI provenance: This post was generated by OpenAI. The original authors did not write or review this post.

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